We present mid-infrared Period-Luminosity relations for Cepheids in the Local Group galaxy IC 1613 . Using archival IRAC imaging data from Spitzer we were able to measure single-epoch magnitudes for five , 7 to 50-day , Cepheids at 3.6 and 4.5 \mu m. When fit to the calibrating relations , measured for the Large Magellanic Cloud Cepheids , the data give apparent distance moduli of 24.29 \pm 0.07 and 24.28 \pm 0.07 at 3.6 and 4.5 \mu m , respectively . A multi-wavelength fit to previously published BVRIJHK apparent moduli and the two IRAC moduli gives a true distance modulus of 24.27 \pm 0.02 mag with E ( B-V ) = 0.08 mag , and a corresponding metric distance of 715 kpc . Given that these results are based on single-phase observations derived from exposures having total integration times of only 1,000 sec/pixel we suggest that Cepheids out to about 2 Mpc are accessible to Spitzer with modest integration times during its warm mission . We identify the main limiting factor to this method to be crowding/contamination induced by the ubiquitous population of infrared-bright AGB stars .