Higher dimensional black holes play an exciting role in fundamental physics , such as high energy physics . In this paper , we use the formalism and numerical code reported in [ ] to study the head-on collision of two black holes . For this purpose we provide a detailed treatment of gravitational wave extraction in generic D dimensional space-times , which uses the Kodama-Ishibashi formalism . For the first time , we present the results of numerical simulations of the head-on collision in five space-time dimensions , together with the relevant physical quantities . We show that the total radiated energy , when two black holes collide from rest at infinity , is approximately ( 0.089 \pm 0.006 ) \% of the centre of mass energy , slightly larger than the 0.055 \% obtained in the four dimensional case , and that the ringdown signal at late time is in very good agreement with perturbative calculations .