We present spectral classifications for 438 B-type stars observed as part of the VLT-FLAMES Tarantula Survey ( VFTS ) in the 30 Doradus region of the Large Magellanic Cloud . Radial velocities are provided for 307 apparently single stars , and for 99 targets with radial-velocity variations which are consistent with them being spectroscopic binaries . We investigate the spatial distribution of the radial velocities across the 30 Dor region , and use the results to identify candidate runaway stars . Excluding potential runaways and members of two older clusters in the survey region ( SL 639 and Hodge 301 ) , we determine a systemic velocity for 30 Dor of 271.6 \pm 12.2 \mbox { km s } ^ { -1 } from 273 presumed single stars . Employing a 3- \sigma criterion we identify nine candidate runaway stars ( 2.9 % of the single stars with radial-velocity estimates ) . The projected rotational velocities of the candidate runaways appear to be significantly different to those of the full B-type sample , with a strong preference for either large ( \geq 345 \mbox { km s } ^ { -1 } ) or small ( \leq 65 \mbox { km s } ^ { -1 } ) rotational velocities . Of the candidate runaways , VFTS 358 ( classified B0.5 : V ) has the largest differential radial velocity ( - 106.9 \pm 16.2 \mbox { km s } ^ { -1 } ) , and a preliminary atmospheric analysis finds a significantly enriched nitrogen abundance of 12 + log ( N/H ) \gtrsim 8.5 . Combined with a large rotational velocity ( v _ { e } \sin i = 345 \pm 22 \mbox { km s } ^ { -1 } ) , this is suggestive of past binary interaction for this star .