Recently , both stellar mass-segregation and binary-fractions were uniformly measured on relatively large samples of Galactic Globular Clusters ( GCs ) . Simulations show that both sizeable binary-star populations and Intermediate-Mass Black Holes ( IMBHs ) quench mass-segregation in relaxed GCs . Thus mass-segregation in GCs with a reliable binary-fraction measurement is a valuable probe to constrain IMBHs . In this paper we combine mass-segregation and binary-fraction measurements from the literature to build a sample of 33 GCs ( with measured core-binary fractions ) , and a sample of 43 GCs ( with a binary fraction measurement in the area between the core radius and the half-mass radius ) . Within both samples we try to identify IMBH-host candidates . These should have relatively low mass-segregation , a low binary fraction ( < 5 \% ) , and short ( < 1 Gyr ) relaxation time . Considering the core binary fraction sample , no suitable candidates emerge . If the binary fraction between the core and the half-mass radius is considered , two candidates are found , but this is likely due to statistical fluctuations . We also consider a larger sample of 54 GCs where we obtained an estimate of the core binary fraction using a predictive relation based on metallicity and integrated absolute magnitude . Also in this case no suitable candidates are found . Finally , we consider the GC core- to half-mass radius ratio , that is expected to be larger for GCs containing either an IMBH or binaries . We find that GCs with large core- to half-mass radius ratios are less mass-segregated ( and show a larger binary fraction ) , confirming the theoretical expectation that the energy sources responsible for the large core are also quenching mass-segregation .