AE Aquarii ( AE Aqr ) is a cataclysmic binary hosting one of the fastest rotating ( P _ { spin } = 33.08 s ) white dwarfs known . Based on seven years of Fermi Large Area Telescope ( LAT ) Pass 8 data , we report on a deep search for gamma-ray emission from AE Aqr . Using X-ray observations from ASCA , XMM-Newton , Chandra , Swift , Suzaku , and NuSTAR , spanning 20 years , we substantially extend and improve the spin ephemeris of AE Aqr . Using this ephemeris , we searched for gamma-ray pulsations at the spin period of the white dwarf . No gamma-ray pulsations were detected above 3 \sigma significance . Neither phase-averaged gamma-ray emission nor gamma-ray variability of AE Aqr is detected by Fermi -LAT . We impose the most restrictive upper limit to the gamma-ray flux from AE Aqr to date : 1.3 \times 10 ^ { -12 } erg cm ^ { -2 } s ^ { -1 } in the 100 MeV \textendash 300 GeV energy range , providing constraints on models .