Inflation predicts that quantum fluctuations determine the large scale structure of the Universe . This raises the striking possibility that quantum mechanics , developed to describe nature at short distances , can be tested by studying nature at its most immense – cosmology . In this note , we realize this possibility . A nonlinear generalization of quantum mechanics modifies predictions for the cosmological power spectrum . Observational cosmology is sufficiently precise to place a stringent limit , b < 3 \times 10 ^ { -34 } eV , on the size of the nonlinear term .