We present results from an observing campaign to identify low-metallicity stars in the Best & Brightest Survey . From medium-resolution ( R \sim 1 , 200 - 2 , 000 ) spectroscopy of 857 candidates , we estimate the stellar atmospheric parameters ( T _ { \mathrm { eff } } , \log g , and [ \mathrm { Fe } / \mathrm { H } ] ) , as well as carbon and \alpha -element abundances . We find that 69 % of the observed stars have [ \mathrm { Fe } / \mathrm { H } ] \leq - 1.0 , 39 % have [ \mathrm { Fe } / \mathrm { H } ] \leq - 2.0 , and 2 % have [ \mathrm { Fe } / \mathrm { H } ] \leq - 3.0 . There are also 133 carbon-enhanced metal-poor ( CEMP ) stars in this sample , with 97 CEMP Group I and 36 CEMP Group II stars identified in the A ( C ) versus [ Fe/H ] diagram . A subset of the confirmed low-metallicity stars were followed-up with high-resolution spectroscopy , as part of the R -process Alliance , with the goal of identifying new highly and moderately r -process-enhanced stars . Comparison between the stellar atmospheric parameters estimated in this work and from high-resolution spectroscopy exhibit good agreement , confirming our expectation that medium-resolution observing campaigns are an effective way of selecting interesting stars for further , more targeted , efforts .