We report 370 measures of 170 components of binary and multiple star systems , obtained from speckle imaging observations made with the Differential Speckle Survey Instrument at Lowell Observatory ’ s Discovery Channel Telescope in 2015 through 2017 . Of the systems studied , 147 are binary stars , 10 are seen as triple systems , and 1 quadruple system is measured . Seventy-six high-quality non-detections and fifteen newly resolved components are presented in our observations . The uncertainty in relative astrometry appears to be similar to our previous work at Lowell , namely linear measurement uncertainties of approximately 2 mas , and the relative photometry appears to be uncertain at the 0.1 to 0.15 magnitude level . Using these measures and those in the literature , we calculate six new visual orbits , including one for the Be star 66 Oph , and two combined spectroscopic-visual orbits . The latter two orbits , which are for HD 22451 ( YSC 127 ) and HD 185501 ( YSC 135 ) , yield individual masses of the components at the level of 2 percent or better , and independent distance measures that in one case agrees with the value found in the Gaia DR2 , and in the other disagrees at the 2- \sigma level . We find that HD 22451 consists of an F6V+F7V pair with orbital period of 2401.1 \pm 3.2 days and masses of 1.342 \pm 0.029 and 1.236 \pm 0.026 M _ { \odot } . For HD 185501 , both stars are G5 dwarfs that orbit one another with a period of 433.94 \pm 0.15 days , and the masses are 0.898 \pm 0.012 and 0.876 \pm 0.012 M _ { \odot } . We discuss the details of both the new discoveries and the orbit objects .