We present proper motion measurements of pre-main sequence ( PMS ) stars associated with major star-forming regions of the southern hemisphere ( Chamaeleon , Lupus , Upper Scorpius - Ophiuchus , Corona Australis ) , situated in the galactic longitude range l = 290 \degr to l = 360 \degr . A list of PMS stars as complete as possible was established based on the Herbig and Bell catalogue and many new catalogues like the PDS survey , the catalogue of Herbig Ae/Be stars by Thé et al . ( [ 1994 ] ) , X-rays surveys , etc . The measurements made use of public material ( mainly AC2000 and USNO–A2.0 catalogues ) as well as scans of SERC–J Schmidt plates with the MAMA measuring machine ( Paris ) and Valinhos CCD meridian circle observations ( Brazil ) . We derived proper motions for 213 stars , with an accuracy of 5 to 10 mas/yr depending mainly on the difference of epochs between the position sources . The main characteristics of the sample are discussed . We show that systematic motions of groups of stars exist , which are not explained by the reflex solar motion .