Large inhomogeneities in neutral hydrogen in the universe can be detected at redshifts z \leq 10 using the redshifted 21 cm line emission . We use cosmological N-Body simulations for dark matter and a simple model for baryonic collapse to estimate the signal expected from structures like proto-clusters of galaxies at high redshifts . We study : ( i ) the standard CDM model , ( ii ) a modified CDM model with less power at small scales , and ( iii ) a \Lambda + CDM model in a universe with \Omega _ { 0 } + \Omega _ { \Lambda } = 1 . We show that it should be possible for the next generation radio telescopes to detect such structures at the redshift 3.34 with an integration of about 100 hours . We also discuss possible schemes for enhancing signal to noise ratio to detect proto-condensates at high redshifts .