We extend previous work showing that violation of the null energy condition implies instability in a broad class of models , including gauge theories with scalar and fermionic matter as well as any perfect fluid . Simple examples are given to illustrate these results . The role of causality in our results is discussed . Finally , we extend the fluid results to more general systems in thermal equilibrium . When applied to the dark energy , our results imply that w = p / \rho is unlikely to be less than -1 .